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KMID : 0882420090770050565
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Korean Journal of Medicine
2009 Volume.77 No. 5 p.565 ~ p.570
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Recent updates on extranodal NK/T-cell lymphoma
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Kim Won-Seog
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Abstract
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Extranodal NK/T-cell lymphoma (ENKL) is a rare subtype of NHL (Non-Hodgkin lymphoma]. It occurs mostly in the nasal and paranal areas. Most of the cases are presented stage I/II. International prognostic index (IPI) can predict the outcome. However, better prognostic model is available such as NKIPI. Because of high expression of p-glycoprotein, ENKL is refractory to chemotherapy. Early stage disease can be bestly treated with concurrent chemoradiation. For advanced stage disease, new clinical trials are now being conducted.
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KEYWORD
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Extranodal NK/T-cell lymphoma
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